Detalhe da pesquisa
1.
Peeking Into the Black Box of T Cell Receptor Signaling.
Annu Rev Immunol
; 2023 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788477
2.
ZAP-70 in Signaling, Biology, and Disease.
Annu Rev Immunol
; 36: 127-156, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29237129
3.
The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P2 replenishment in response to TCR signaling during T cell development and survival.
Nat Immunol
; 24(1): 136-147, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36581712
4.
A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.
Nat Immunol
; 24(4): 676-689, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914891
5.
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
Nat Immunol
; 24(1): 174-185, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36564464
6.
TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.
Immunity
; 56(12): 2682-2698.e9, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091950
7.
Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.
Nat Immunol
; 20(11): 1481-1493, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611699
8.
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.
Nat Immunol
; 19(7): 733-741, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29915297
9.
Insights into the initiation of TCR signaling.
Nat Immunol
; 15(9): 798-807, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25137454
10.
Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210.
Nat Immunol
; 15(4): 393-401, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24608041
11.
Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling.
Nat Immunol
; 15(2): 186-94, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24317039
12.
Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development.
Nat Immunol
; 15(7): 687-94, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24908390
13.
Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology.
Trends Immunol
; 44(4): 248-255, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36907684
14.
Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells.
Proc Natl Acad Sci U S A
; 120(25): e2300987120, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37307442
15.
ZAP70, too little, too much can lead to autoimmunity.
Immunol Rev
; 307(1): 145-160, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923645
16.
Positive Regulation of Lyn Kinase by CD148 Is Required for B Cell Receptor Signaling in B1 but Not B2 B Cells.
Immunity
; 45(6): 1232-1244, 2016 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27889108
17.
CD28 Costimulation: From Mechanism to Therapy.
Immunity
; 44(5): 973-88, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27192564
18.
A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45.
Mol Cell
; 67(3): 498-511.e6, 2017 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28735895
19.
Digital signaling and hysteresis characterize ras activation in lymphoid cells.
Cell
; 136(2): 337-51, 2009 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19167334
20.
Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway.
Proc Natl Acad Sci U S A
; 118(43)2021 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34675079